Thursday, March 28, 2024

Aspirin can also provide cancer prevention benefits

Imagine that after years of painstaking research, scientists announced the development of a breakthrough treatment that costs pennies a pill, saves lives, and could reduce healthcare spending by nearly $700 billion in the coming years. And you wouldn’t even need a prescription to get it. Perhaps this all sounds too good to be true. But, according to a new study, we already have such a drug: it’s called aspirin.

An analysis of aspirin use

Based on current recommendations, only about 40% of people who should be taking aspirin are doing so. In this new report, researchers asked: what might happen to population health, longevity, and healthcare costs if aspirin use were more widespread? To answer this, they analyzed reams of health data from thousands of patients and estimated the impact of more widespread aspirin use on their health and survival.

Their findings were striking. For people in the U.S. ages 51 to 79, routine aspirin use could, over a 20-year period:

  • prevent 11 cases of heart disease for every 1,000 persons
  • prevent four cases of cancer for every 1,000 persons
  • lengthen national life expectancy by about four months, allowing an extra 900,000 people to be alive in 2036
  • save $692 billion.

Is there a downside to aspirin?

As is true for all medications, aspirin has its downsides. Among other side effects, allergic reactions may occur. And, aspirin is a blood thinner and can irritate the stomach. Episodes of bleeding and stomach ulcers can be serious. So, the researchers took these into account; the estimates above include these side effects of taking aspirin.

It’s important to emphasize that this study assessed the impact of low-dose aspirin, such as the 85 mg daily dose often found in baby aspirin; higher doses may be recommended for other conditions (and come with added risk). In addition, aspirin can interact with other medications. For example, if you take low-dose aspirin for your heart and ibuprofen for arthritis, it’s important that the ibuprofen be taken at least 30 minutes after or more than eight hours before the aspirin; otherwise, the benefit of the aspirin may be lost.

Read more of the article by Robert H. Shmerling, MD, Faculty Editor, Harvard Health Publications here.

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